Tuesday, July 31, 2012

petergardett: Focusing on #cleantech at the London version of Silicon Valley (jobs too, of course) http://t.co/mOpJuwLq via @AOLEnergy #energy startups

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Source: http://twitter.com/petergardett/statuses/230041432117891072

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In Jerusalem, the Mitt fits (Powerlineblog)

Share With Friends: Share on FacebookTweet ThisPost to Google-BuzzSend on GmailPost to Linked-InSubscribe to This Feed | Rss To Twitter | Politics - Top Stories Stories, News Feeds and News via Feedzilla.

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Poll: Tea Party Favorite Cruz Leads Heading into Texas GOP Showdown

In a much-watched Senate race in Texas seen as a battle between the tea party and the Republican establishment, a new poll shows tea party favorite Ted Cruz with a 10-point lead over incumbent Lieutenant Governor David Dewhurst just ahead of Tuesday?s runoff election.

Dewhurst won the May 29 primary by 10 points in the race to replace retiring GOP Sen. Kay Bailey Hutchison, but failed to get an outright majority.

The new survey conducted by Public Policy Polling (PPP) shows former state Solicitor General Cruz with 52 percent of the vote to 42 percent for Dewhurst, the traditional Republican choice.

And Cruz is far ahead among tea party voters, by a 75-percentage-point to 22-point margin, according to PPP, while Dewhurst leads 56 to 39 percent among voters who don?t consider themselves members of the tea party movement.

The Dewhurst campaign insists it is ahead, citing an internal poll showing him leading Cruz 48 percent to 43 percent.

PPP also found that Republican runoff voters are more likely to vote for a candidate backed by Sarah Palin, who supports Cruz, rather than a candidate backed by Texas Gov. Rick Perry, who is supporting Dewhurst.

Thirty-one percent of respondents say they would vote for a candidate endorsed by Palin, while 16 percent are more likely to vote for Perry?s choice.

?Palin and Perry both have strong sway with the tea party movement, and the Texas GOP runoff has been billed as a battle between the tea party and the Republican establishment,? USA Today observed, noting that the runoff is ?a sign of the ?maturing? of tea party forces.?

Perry is appearing with Dewhurst at a veterans group in San Antonio on Monday, then the pair will hold a fundraiser and visit a Dewhurst campaign phone bank in Dallas.

The two other candidates Dewhurst beat in the primary, former Dallas Mayor Tom Leppert and former ESPN analyst and college football star Craig James, are also campaigning for Dewhurst.

But several prominent politicians from outside Texas are actively supporting Cruz. Sen. Jim DeMint, R-S.C., ?would like to add the tea party-backed Cruz to a cadre of senators trying to push the GOP agenda further right,? the San Antonio Express-News reported.

?Every Senate race is a national race,? DeMint declared.

Republican Sen. Paul Rand of Kentucky, who grew up in Texas, has campaigned for Cruz, as has Sen. Mike Lee of Utah, who lived in Texas for two years.

Two Democrats are also involved in a runoff on Tuesday.

Cruz?s strong showing despite Gov. Perry?s backing of Dewhurst is ?indicative of Perry?s diminished political standing in Texas after his failed presidential bid,? PPP states.

?And if Cruz really does end up winning big on Tuesday, it raises questions about whether [Perry] would be able to survive a strong Republican primary challenge in 2014.?

? 2012 Newsmax. All rights reserved.

Source: http://www.newsmax.com/Politics/cruz-dewhurst-texas-republican/2012/07/30/id/447029

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Monday, July 30, 2012

Copyright Olympics: The App Store's 8 cheekiest London 2012 cash-ins

The Olympics brand police are currently running around London in Adidas trainers with Samsung smartphones, dousing Londoners in Coca-Cola while shoving McDonald's fries into the stunned, open mouths of any onlookers.

London 2012 - The Official Video Game of the Olympic Games Screenshot
Official branding is important to the powers that be at LOCOG, prompting it to release a list of phrases prohibited from use without its say-so. They are:

  • "Olympic", "Olympian", "Olympiad", "Paralympic", "Paralympian", "Paralympiad" their plurals, translations and anything similar to them.
  • "Backing the 2012 Games", "Supporting the London Games"
  • Any two List A words or any word from List A and List B in the same sentence:
    • LIST A: "Games", "Two Thousand and Twelve", "2012", "Twenty-Twelve"
    • LIST B: "London", "medals", "sponsors", "summer", "gold", "silver", "bronze"

Here, we celebrate the App Store games happily sticking two fingers in the direction of LOCOG's brand guidelines in order to milk Olympic fever in a number of increasingly creative ways. We've even awarded them Gold, Silver and bronze medal later on. Take that, The Man...

8th: ZooOlympic

London 2012 - The Official Video Game of the Olympic Games Screenshot
Zoo Olympic's events include Sea Escape, Enjoy Flying, Memory Card and Eat Meat - therefore using the word Olympic at the risk of enraging LOCOG for almost no reason at all. We respect this level of flippancy.

Source: http://rss.computerandvideogames.com/c/674/f/8604/s/21d989af/l/0L0Scomputerandvideogames0N0C360A5960Cblog0Ccopyright0Eolympics0Ethe0Eapp0Estores0E80Echeekiest0Elondon0E20A120Ecash0Eins0C0Dcid0FOTC0ERSS0Gattr0FCVG0EGeneral0ERSS/story01.htm

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Switched On: For OUYA, it's game on

Each week Ross Rubin contributes Switched On, a column about consumer technology.

DNP Switched On For Ouya, it's game on

In discussing the varied routes Android has taken to the television, Switched On recently touched on OUYA, the cuboid game console that will run free-to-play Android games. The project has surpassed the $5.5 million mark on Kickstarter and once seemed poised to pass the Pebble smartwatch's record for overall funds collected just like it broke the record for funds collected in the first day.

Continue reading Switched On: For OUYA, it's game on

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Switched On: For OUYA, it's game on originally appeared on Engadget on Sun, 29 Jul 2012 17:30:00 EDT. Please see our terms for use of feeds.

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Sony Cuts Some Corners, Delivers an $800 Ultrabook

Sony's Vaio T Series is more restrained than the company's other notebooks, offering a slimmed-down computing experience complete with third-generation Core i5 CPU for just 800 bones.

Source: http://feedproxy.google.com/~r/GearFactor/~3/UmwkS2Vfdg8/

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Sunday, July 29, 2012

Arcana Power

Arcana Power

The world is ruled by the Arcana, and the embodiments of these mighty powers will raise to fulfill the worlds final fate.

Owner:

Game Masters:

This topic is an Out Of Character part of the roleplay, ?Arcana Power?. Anything posted here will also show up there.

Topic Tags:

Forum for completely Out of Character (OOC) discussion, based around whatever is happening In Character (IC). Discuss plans, storylines, and events; Recruit for your roleplaying game, or find a GM for your playergroup.
This is the auto-generated OOC topic for the roleplay "Arcana Power"

You may edit this first post as you see fit.

User avatar
ponerj
Member for 3 years



i would like to reserve the mage. also what anime is your pic from [=

FEAR ME LOVE ME FOR I AM YOUR KING
User avatar
dimon lord
Member for 0 years


I want The Death Arcana,
@dimon lord is Yumekui Merry

"The laziness is the engine of progress, who invented the wheel was because, obviously, didn't want walk"

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Fencer
Member for 0 years


Can i reserve wheel of fortune Arcana

User avatar
ali_rox96
Member for 0 years



Post a reply

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Friends defend man held in Md. shooting plot

WASHINGTON (AP) ? To his friends, Neil E. Prescott was a "gentle giant" ? a physically towering young man with a background in computers and electronics and a sarcastic, even biting, sense of humor that people close to him knew to shrug off as innocuous.

But police say they had no choice but to take it seriously when Prescott threatened to shoot up his workplace and referred to himself as "a joker," comments that raised particular alarm in the wake of last week's mass shooting at a Colorado theater during the latest Batman movie. The man accused in those shootings dyed his hair reddish-orange, and New York Police Commissioner Ray Kelly has said the man called himself the Joker ? a reference to Batman's nemesis.

Prescott, 28, was taken into custody early Friday at his apartment in Maryland, where officers found several thousand rounds of ammunition and a cache of about two dozen weapons including semi-automatic rifles and pistols. He was receiving an emergency psychiatric evaluation at a hospital and had not been charged as of Saturday afternoon.

Two friends told The Associated Press Saturday that they couldn't imagine that Prescott, who was in the process of being fired or already had lost his job, intended to be taken seriously when he allegedly told a supervisor: "I'm a joker and I'm gonna load my guns and blow everybody up."

"Neil's the kind of guy who had the ability to say the wrong thing at the wrong time and not mean anything by it. So to him, he thinks it's funny," said Wesley Weber, who said his friend, at 6 feet 7 inches, was a "gentle giant" prone to bouts of exaggeration and inappropriate jokes who "talked big but didn't walk the walk."

"He has the ability," Weber added, "to say things that could be taken out of context."

Another friend, Mike Cochran, said Prescott has a history of wearing T-shirts with sarcastic, provocative and even inflammatory messages and is "no stranger to sarcasm regardless of political correctness." When first approached by officers, police say, Prescott was wearing a shirt that said "Guns don't kill people. I do."

"The Neil I know made those comments sarcastically in an environment where he felt he could make them without being taken seriously," Cochran said in an email.

Friends say that over the years, Prescott had shown deep interest in hobbies like such as computer software, electronics and ham radio. His clique of friends at one time gathered at parties to play multi-player video games and consume the highly caffeinated Jolt cola, Weber recalled. A sometime disc jockey, he'd also spin house music at Baltimore nightclubs and was the DJ for Cochran's bachelor party in 2005.

In recent years, though, he'd cultivated a passion for collecting firearms. He'd practice his shot at the training range, friends said, and communicate online with fellow gun enthusiasts about the ins and outs of firearm equipment and gun laws. At least some of the firearms recovered from his apartment in Crofton, near Annapolis, appear to have been legally owned, authorities said.

A search for Neil Prescott on a website that tracks users' online activities led to a profile that appears to be him on mdshooters.com, a website for Maryland gun hobbyists. On it, he trades advice about firearms with a display of technical know-how while at times expressing concern about break-ins near his apartment and detailing interactions with the police.

Cochran, who also posts on the site, said he doesn't know when Prescott started his gun collection but that he had been anxious about home invasions. He said he received one message from Prescott last November that said, "Might be sleeping in tomorrow, just had a suspicious male at my door. Notified PD but am gonna be lookin out tonight. Some crazy breakins near me recently."

In March, he provoked a spirited back-and-forth on the site when he complained that two police officers responding to a possible break-in at a nearby apartment "told me never to answer the door on my own property carrying." He said he called a sergeant to complain about the directive.

Last week, he was still on the site, talking with fellow users about 30-round magazines and boasting about his night-vision goggles.

"During the power outage i spent lots of time loading mags and mounting lights, when the zombie apocalypse comes i'll be ready," he wrote.

Maryland state court records for Prescott list only a speeding ticket in 2007. It wasn't immediately clear if he had a lawyer.

Police say Prescott, an employee of a subcontractor for software and mailroom supplier Pitney Bowes, made the threats during two Monday morning phone conversations with a supervisor. The supervisor, who declined to comment Saturday to a reporter who came to his house, said the comments made him afraid, especially because he was aware of Prescott's weapons' cache.

Prescott at one point said he wished to see his supervisor's "brain splatter all over the sidewalk," but also acknowledged that he shouldn't be saying such things over the phone, according to a search warrant applications. The threats were reported to the police, who paid an initial visit to Prescott's apartment on Thursday before taking him into custody Friday morning.

Cochran said he's known Prescott since 2001, when they were colleagues at a technical support outsourcing company. He said Prescott was a network engineer.

"With his skill set and education he would have had no problems finding other work with good pay. Neil did not at any point indicate to me that he had problems with where he was working," Cochran wrote.

Pitney Bowes spokeswoman Carol Wallace said Prescott had not been on any company property in at least four months. It wasn't clear why he was losing his job.

Weber said he thought the remark was inappropriate, but that it was bound to receive more attention now than it may have years ago, especially one week after the Colorado shooting.

"We live in a different world now," he said.

___

Follow Eric Tucker on Twitter at http://twitter.com/etuckerAP

___

Associated Press writer Brian Witte and AP researcher Judith Ausuebel contributed to this report.

Source: http://news.yahoo.com/friend-md-man-held-shooting-plot-gentle-giant-154103620.html

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Amazon - Marley - Medium - Adult - Female - Bird | Melbourne ...

Amazon - Marley - Medium - Adult - Female - Bird

Marley is an Amazon. She is a good bird and has never bitten anyone, ever. She appears to have some sight issues which cause her to be afraid of to much motion. When approached by voice she is much calmer and does not squak so much. She is really a great bird for that perfect someone. I do not think active children around or other parrots would be good for Marley. Her fee is $275.00 Please see the company info for all information on adopting this or any bird from M.A.R.S.

CHARACTERISTICS:
Breed: Amazon
Size: Medium
Petfinder ID: 23649282

CONTACT:
Melbourne Avian Rescue Sanctuary | Melbourne Beach, FL

For additional information, reply to this ad or see: http://www.petfinder.com/petnote/displaypet.cgi?petid=23649282

Brought to you by Petfinder.com

Source: http://palmbay.ebayclassifieds.com/birds/melbourne-beach/amazon-marley-medium-adult-female-bird/?ad=21855137

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Saturday, July 28, 2012

Improvements To Increase The Energy Efficiency Of Your Home ...

When it is time to make serious improvements to your home, engage the services of a competent general contractor. Shop around and make careful comparisons. A competent and honest, general contractor, can complete home improvements professionally. A contractor can also perform home improvement work cheaper than you can manage, by doing it yourself.

Choose stains, paints, glues, and sealants which are produced in a manner that won?t release chemicals into your air when you use them. Look for low No-VOC items, but also try to find paints made with milk protein, clay, earth pigments, or lime. Stains can be made with linseed or citrus oil.

If you?re looking for a low cost way to improve the look of your home?s interior, add a fresh coat of paint. Make sure you choose a neutral color. Dark or drab colors can make a room feel oppressive and confining. Painting with neutral colors will give rooms a fresh, airy feeling of openness.

If you have a home improvement project, why not involve the neighbors? Look into tool borrowing websites to borrow goods from your neighbors. You can borrow expensive tools for just a fraction of the cost; saving you lots of money, and enabling you to have the tools you need when you need them. Bonus! You get to meet and know your neighbors, making your neighborhood a better, happier place to live.

Consider adding an extra bathroom to boost the value of your home. Even if you do not plan on using it except when you have a guest over, the expenses linked to an additional bathroom are definitely worth it. If you have a house with two levels, build the bathrooms on top of one another to save on plumbing.

If you are hiring someone to perform your home improvement work, never pay more than 10% down or $1000, whichever sum is less. Legally, a contractor is not able to accept more than this figure. If he asks for additional funds, it is a sign that the person you hired may not be very reputable.

Are you planning a big home improvement project that requires a lot of hard manual labor that you cannot do alone? One way to get the job done while also saving money is to use temporary laborers from a service. You can choose how many experienced people you need and what time they will arrive and leave each day.

If you find yourself falling in love with a particular pattern of wallpaper but find that it?s either out of your price range or not quite durable enough for high-traffic areas, consider buying a roll of it anyway for decorative purposes. You can easily have it matted and framed, or can keep it around the house for smaller, more craft-type projects.

Wallpaper borders are no longer as popular as they once were. However, you can add nice designs to your wall without them. Buy some stencils at your local craft store in a theme that matches your home decor and paint them in a line on your wall where normally the wallpaper border would go. This creates a nice visual effect for your eyes to follow in the room.

If you don?t already have some, install some ceiling fans in all your rooms. You can use these to cool rooms and circulate the air, reducing the need to use your air conditioning unit. This in turn will save you money on your electric bill and most likely increase the life expectancy of your air conditioner.

When it comes to home improvement, small things such as replacing your central air blower?s air filters are essential. This is important both to the efficiency of the blower, as well as being a necessary maintenance procedure. If you allow dust and dirt to gather and even bypass the filter, it will gather within the moving parts of the blower and eventually cause it to fail.

If you browse through the tips from this site, you are sure to find a tip that can bring your home to a whole new level of beauty. If you apply some of these tips today, your home will be on its way to truly being improved.

Adrian Erling researches reverse osmosis water purification

Source: http://www.techreviewsworld.com/?p=37830

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Ways In Which The Identity Theft Deterrence Act Can Assist Victims Of


Legal | Identity Theft | * Written by Daryl | Friday, 27 July 2012 01:58 | Word Count: 471

Gartner Inc, a giant in the research field, estimates that only one out of seven hundred people who commit identity fraud ever gets brought to justice. In Medford Oregon recently they apparently found the one. The Associated Press reported one one identity theft criminal that arrived at a local bank to cash a check. What makes this story so bizarre is the thief was caught by the person he had been victimizing. Apparantly they were in the same bank at the exact same time as the thief. The victim was there ironically enough to dispute the previous bogus charges.

Unfortunately for many others who have had their identity stolen there's no chance of them coming face to face with the thief and by some miracle apprehending them. Identity fraud is a crime that affects over 8 million people per year. While check fraud and other forms of identity theft have seen a sharp dropoff others such as phishing websites are rising at record levels. The breakneck speed of technological innovations is making identity theft easier and easier.

The ability to steal personal information has also reached cell phone users where downloading certain apps can result in sensitive data you've stored in your phone getting hijacked and sent to remote servers where thieves are waiting to record that information such as online banking logins and password.

The good thing is there are resources out there which can be of great assistance. In 1998 The U.S. Congress passed the Identity Theft and Assumption Deterrence Act. This made identity theft a federal offense and with it comes harsher penalties any time identity thieves are seized and found guilty.

It also put the Federal Trade Commission commonly referred to as the FTC at the vanguard of combating identity theft. The FTC and in particular their internet site is loaded with information and facts including prevention, video and news item updates. Over the last 10 years they've done a remarkable job in their work to teach the general public on exactly how engraved this crime has become in this country as well as the measures essential to protect against it.

A key component was the development of the Identity Theft Clearinghouse data bank. It is an online repository designed to help local and federal law enforcement officials. Each and every complaints regarding identity theft are promptly recorded into the data bank which is kept up to date constantly.

One final thing this legislation has done to help consumers with any credit issues they may have trouble resolving. Even when they are fully aware you've been the victim of identity fraud credit agencies for reasons all their own are still slow to act in the case of eliminating it from your personal records. This process can sometimes get expedited when you have the federal government backing you up.

For more information check out id theft and fraud information

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Author of this article: Daryl.

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Daryl joined FAFY - Free Article For You on Wednesday, 29 February 2012.

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Friday, July 27, 2012

U.S. fears Syria is plotting a massacre

AMMAN/BEIRUT (Reuters) - President Bashar al-Assad's forces renewed a ground and aerial bombardment of Aleppo on Friday, extending efforts to crush rebels in Syria's commercial capital in what the United States said it feared could become a massacre.

Insurgents targeted army roadblocks and security installations, with both sides avoiding close-quarters warfare in the city of 2.5 million people, Syria's biggest urban center.

The U.S. State Department said credible reports of tank columns moving on Aleppo, along with air strikes by helicopters and fixed-wing aircraft, represented a serious escalation of Assad's efforts to crush a rebellion that began 16 months ago.

"This is the concern: that we will see a massacre in Aleppo, and that's what the regime appears to be lining up for," State Department spokeswoman Victoria Nuland said.

Troops stationed on the outskirts of Aleppo unleashed barrages of heavy-caliber mortar rounds on the western neighborhoods of Saladin, al-Sukkari and al-Fardos, while Russian MI-25 helicopter gunships struck al-Sakhour in the east with rockets, several opposition activists in the city said.

RISING CASUALTIES

In the first reported casualty on Friday, a man of about 60 wearing a traditional white prayer outfit was killed near a park in Saladin. His body was placed in a mosque pending identification.

Thirty-four people were killed in Aleppo and its environs on Thursday, according to opposition activists keeping a tally of casualties in the northern city.

"The rebels have so far been nimble, and civilians have mostly been the victims of the bombardment," said activist Abu Mohammad al-Halabi, speaking by phone from the city.

"There is lots of internal displacement, and schools have been turned to makeshift shelters that are packed. One shell hitting a school will result in a catastrophe," he said.

"The regime is massing troops and tanks at the entrances of Aleppo, but it seems it is for now content with bombarding the city, with the rebels constantly on the move."

Majed al-Nour, another activist, said rebels attacked a security outpost in the neighborhood of Bustan al-Joz, which is close to the Aleppo city center, on Thursday.

"The rebels are present in the east and west of the city, and have a foothold in areas of the center. The regime forces control the entrances of Aleppo and the main thoroughfares and commercial streets and are bombarding the residential districts that fell into rebel hands," he said.

Nour said tens of thousands of people had fled Aleppo to nearby northern rural regions close to Turkey from which the Syrian army has withdrawn in recent weeks to focus on urban areas where relatively lightly armed rebels have hunkered down.

UNITING THE OPPOSITION

The heavy fighting around Aleppo follows an audacious bomb attack that killed four of Assad's closest lieutenants in Damascus on July 18 and led some analysts to speculate that the government's grip was slipping.

With U.N. Security Council resolutions for sanctions against Syria vetoed by Russia and China for a third time last week, the United States has said it is stepping up assistance to Syria's fractured opposition, although it remains limited to non-lethal supplies such as communications gear and medical equipment.

One of the most senior figures to defect from Assad's inner circle, Brigadier General Manaf Tlas, put himself forward on Thursday as someone who could help unify the opposition inside and outside Syria on a plan for a transfer of power.

Tlas, speaking in a newspaper interview in the Saudi city of Jeddah, also said he was looking for support from Saudi Arabia and other powers. "I am discussing with ... people outside Syria to reach a consensus with those inside," Tlas told Thursday's edition of the Saudi newspaper Asharq al-Awsat.

Tlas went on to Turkey and met with Foreign Minister Ahmet Davutoglu. Turkey, a former ally of Assad and now one of his fiercest critics, has a heavy strategic stake in shaping any post-Assad leadership in neighboring Syria.

Tlas appeared briefly with Davutoglu at an official guest house, but made no statement.

Turkey closed its border posts with Syria on Wednesday to all traffic except Syrian refugees.

Russia, one of the few remaining allies of the authoritarian Assad whose family has run Syria for 42 years, said calls for him to quit power were hindering efforts to end the conflict.

Foreign Minister Sergei Lavrov said such calls, led by the United States, Turkey and other Western and Arab nations, were fanning violence. He reiterated Moscow's contention that support for Syrian rebel groups was tantamount to backing terrorism.

Iran promised to stand by Syria, come what may.

First Vice President Mohammad Reza Rahimi told Iran's Press TV on Thursday that the Islamic Republic's support for Syria, its main Arab ally, was "unchangeable", countering suggestions that Iran could soften its backing for Assad.

(Writing by Will Waterman; Editing by Mark Heinrich)

Source: http://news.yahoo.com/syrian-forces-pound-aleppo-damascus-083803528.html

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A mouse model for triple-negative breast cancer tumor-initiating - GMD

Kau P, Nagaraja GM, Zheng H, Gizachew D, Galukande M, Krishnan S, Asea A.

BMC Cancer. 2012 Mar 27;12:120.

Department of Pathology, Scott & White Memorial Hospital and Clinic and the Texas A&M Health Science Center, College of Medicine, Temple, TX 76504, USA. asea@medicine.tamhsc.edu

Abstract

BACKGROUND:

Triple-negative breast cancer (TNBC) exhibit characteristics quite distinct from other kinds of breast cancer, presenting as an aggressive disease?recurring and metastasizing more often than other kinds of breast cancer, without tumor-specific treatment options and accounts for 15% of all types of breast cancer with higher percentages in premenopausal African-American and Hispanic women. The reason for this aggressive phenotype is currently the focus of intensive research. However, progress is hampered by the lack of suitable TNBC cell model systems.

METHODS:

To understand the mechanistic basis for the aggressiveness of TNBC, we produced a stable TNBC cell line by sorting for 4T1 cells that do not express the estrogen receptor (ER), progesterone receptor (PgR) or the gene for human epidermal growth factor receptor 2 (HER2). As a control, we produced a stable triple-positive breast cancer (TPBC) cell line by transfecting 4T1 cells with rat HER2, ER and PgR genes and sorted for cells with high expression of ER and PgR by flow cytometry and high expression of the HER2 gene by Western blot analysis.

RESULTS:

We isolated tumor-initiating cells (TICs) by sorting for CD24+/CD44high/ALDH1+ cells from TNBC (TNBC-TICs) and TPBC (TPBC-TICs) stable cell lines. Limiting dilution transplantation experiments revealed that CD24+/CD44high/ALDH1+ cells derived from TNBC (TNBC-TICs) and TPBC (TPBC-TICs) were significantly more effective at repopulating the mammary glands of naive female BALB/c mice than CD24-/CD44-/ALDH1- cells. Implantation of the TNBC-TICs resulted in significantly larger tumors, which metastasized to the lungs to a significantly greater extent than TNBC, TPBC-TICs, TPBC or parental 4T1 cells. We further demonstrated that the increased aggressiveness of TNBC-TICs correlates with the presence of high levels of mouse twenty-five kDa heat shock protein (Hsp25/mouse HspB1) and seventy-two kDa heat shock protein (Hsp72/HspA1A).

CONCLUSIONS:

Taken together, we have developed a TNBC-TICs model system based on the 4T1 cells which is a very useful metastasis model with the advantage of being able to be transplanted into immune competent recipients. Our data demonstrates that the TNBC-TICs model system could be a useful tool for studies on the pathogenesis and therapeutic treatment for TNBC.

Go To PubMed

Source: http://globalmedicaldiscovery.com/key-scientific-articles/a-mouse-model-for-triple-negative-breast-cancer-tumor-initiating-cells-tnbc-tics-exhibits-similar-aggressive-phenotype-to-the-human-disease/

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Thursday, July 26, 2012

Cracking Up: Cracking Up: Remembering Grandpa Mac


as published at www.ocregister.com on July 25th, 2012:

"Don't bend the cards."

I'll never hear that phrase again without thinking of my Grandpa Mac. Last week, he became my first grandparent to pass away.

Not only were we not to bend the cards while shuffling, but Grandpa's voice will live on to remind us not to "play out of turn" and to avoid unscrupulous "table talk" with our partner while playing his favorite card game: Hand and Foot.At his funeral, many of his trademark phrases were shared over the podium as his five kids took turns remembering him, and the congregation of his life chuckled knowingly as we predominately heard catchphrases sputtered from his role as officiator of thousands of family card games.

Going to Grandpa and Grandma Mac's for dinner the second Sunday of the month was a ritual for many of their 21 grandkids who circulated through their town while attending college. And just as we knew Grandma would always serve her delicious soft rolls, homemade jam, and Jello topped with whipped cream, we knew as soon as the table was cleared of dishes, a box of Rook cards would fill their void. Grandpa would then shuffle and disperse the cards with the skill of a Vegas dealer as our eyes assessed our hand's ability to win the round, and our ears perked up to his jocular pre-game banter and occasional break into song.

However, once the first card was flipped, the game was on and so better had you be...

Read the rest:

Cracking Up: Remembering Grandpa Mac - OC Moms - The Orange County Register

Source: http://crackingupmotherhood.blogspot.com/2012/07/cracking-up-remembering-grandpa-mac.html

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Mary Kay spokesman defends company's direct sales business model

Just in time for the gathering of 30,000 pink ladies at the Dallas Convention Center, KERA?s ?Think? piece today focused on Addison-based Mary Kay and the business of beauty, from the standpoint of the independent sales consultants.

Featured guests included?investigative reporter?Virginia Sole-Smith, whose piece ?Pink Pyramid Scheme: How Mary Kay cosmetics preys on desperate housewives? appears in the August, 2012 issue of Harper?s Magazine.

Offering a strong rebuttal was Crayton Webb,?Mary Kay?s?Director of Corporate Communications and Corporate Social Responsibility.

?

This entry was posted in Retail and tagged Mary Kay by Karen Robinson-Jacobs. Bookmark the permalink.

Source: http://bizbeatblog.dallasnews.com/2012/07/mary-kay-spokesman-defends-companys-direct-sales-business-model.html/

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What do you must know about canon 5d mark iii prior to when buy the

These Canon 5d mark iii is usually a camcorder built from Canon: item has got a 5X visual zoom lens do the job; it?s just a 9 megapixel surveillance camera, additionally it athletics a fabulous vari-angled Three.Seven wriggle broad LCD display. Within the Canon 5d mark iii can be a DIGIG Six design which in turn would ensure very intense making of all pictures and also stills. Even greater, Canon carries designed a HS Solution into the Canon 5d mark iii in addition: the later feature makes certain that along with the particular regarding lamps and lights every stills can be correctly grabbed. Internet sites the actual Canon 5d mark iii will often recognize the value of the chance to obtain motion picture clips plus online video media, all of the inside 720p selection. Even further, while using the listed Hdmi program, a computer owner of your 5d mark iii can view film fastens on your home pc or perhaps on your no matter what the television overly.

Your Canon 5d mark iii is actually a top-quality small in size equipment: it has got additional a lot of creations when it is compared instantly to it has the forerunner this G11 of your remarkable PowerShot model. Item not simply sustains the first, key operates for the G11, the application brings at a Hybrid IS for lovely similar pros, we have an introduced EOS taste management face for the prominent on the piece of equipment, plus Canon has put in SDXC business card baby stroller and additionally multi-aspect facteur filming characteristics.

That 5d mark iii professional sports the latest 29 to help 135 millimeter identical website, a rotating Liquid crystal display meant for comfort of area of interest browsing, Tender taking pictures performs, and even many different information in addition to easy equipment. Typically the 5d mark iii incorporates an out of astounding accessory solution, an expensive strong span relation, good car and motorbike offers, an important CCD probe / sensor in, in addition to pictures can be seized within the array of file sizes along with capacities. Wonderful features, through collecting dvd stuff that can be done within Hrs an and Thirty frames per second! You will get considerable time and far more with an investment in your 5d mark iii; item is definitely really extremely sunshine, portable, and it?s effortless to carry along with regardless of where you?d like on-going.

These Canon 5d mark iii will allow you to grab 60 minute block size show films. Pictures seem to be placed in JPEG and additionally Natural sizes and movies are input into Transport platforms. This method camera system has every one of the superb supplements overly including shot stabilization, auto-focus, are up against prognosis, handheld Four times the lens quality, guide focal point, persistent taking, picture tracking, a vast ISO degree of selection, AE Lck, including a 15-1/4000 further shutter accelerate. This unit has a sensible shutter, an important are up against own cooking timer, an important wink auto cooking timer, lots more market processes, and several special effects with regard to innovative photo making businesses.

It doesn?t matter if you want to capture rrmages for extreme distinction surroundings or you would like to get the cheapest closure, this Canon 5d mark iii is an ideal digital camera resolution. You can acquire amazing images, awesome certain video clips, numerous experts be sure each random access memory you will seize gets nearer existence totally tint when you?ve got nailed the memories while using the 5d mark iii. You can obtain all of the 5d mark iii with an historical cheap price very: which you find in you an outstanding expenditure of money over everything.

Even if you want to take snapshots on extraordinary comparison places or your are checking into benefit from the best close, a Canon 5d mark iii is the best dslr camera choice. Drop by my personal how do people find more detailed info about that dslr camera. I really appreciate your opportunity to chech this short article. Best wishes!

Source: http://articlereference.net/reference-education/what-do-you-must-know-about-canon-5d-mark-iii-prior-to-when-buy-the-situation.html

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Video: Let the Games begin?

Killers' parents become instant pariahs

Like the parents of Tucson gunman Jared Loughner, Oklahoma City bomber Timothy McVeigh and Columbine High School killers Dylan Klebold and Eric Harris, the parents of accused movie theater shooter James Eagan Holmes have been publicly reviled for raising a murderer.

Source: http://www.msnbc.msn.com/id/3036697/vp/48328215#48328215

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Finding Extra Money to Save for Retirement | Ellwood City News

Chances are you would like to be able to save more money each month toward your retirement or other financial goals. Who couldn?t use a little more? Given the reality of lower interest rates and investment returns that many have experienced in recent years, simply saving more money is the key to building a sufficient nest egg for retirement. But unfortunately it?s not so simple to come up with the extra cash to sock away.

It may be challenging, but not impossible. Start by looking at it this way; if you decide to set aside another $100 per month for your retirement, it amounts to $3.33 per day. If you?d like to be more aggressive and save an extra $500 per month ? you would need to set aside $17 per day or about $120 each week. In some cases, saving these manageable amounts daily can add up ? and lead to a more secure financial future. Here are a few savings opportunities to consider:

Refinancing your mortgage

If the equity position in your home is favorable and you are paying interest on your mortgage at a rate that is noticeably higher than today?s low rates, refinancing could save you a significant amount on your mortgage. The way to benefit the most from refinancing is not to increase your spending on other things, but to invest each dollar saved in a retirement plan or to help you fund other financial goals.

Changing your tax withholding

According to the IRS, as of the end of April 2012, the average tax refund paid on a 2011 tax return was $2,700. If you are consistently receiving a sizable refund and don?t anticipate major changes in your income or deductions claimed on a tax return, you can adjust the amount withheld from your paycheck. Talk to your employer about completing a new W-4 form, and put your bigger paycheck to good use.

Reducing gas costs

With gas prices hovering around $3 to $4 or more per gallon, it?s become more expensive to drive. Cut back on unnecessary driving and consider finding alternative ways to get to work such as public transit. Walk and bike more to nearby places. More careful use of vehicles could generate $50 to $100 extra dollars each month.

Managing your food budget

Food can be one of the biggest expenses for a family. Better meal planning can help you stretch your grocery dollars by reducing the amount of food you throw out and the number of times you pay for meals at restaurants. In addition, think about other ways to cut back, such as eating fewer lunches out during the week or cutting back on expensive coffee drinks that can easily add up.

Identifying home expenses you can live without

Many of us pay exorbitant bills for services like cable or satellite TV without actually using the service enough to justify the expense. Consider whether a movie rental service might be a cheaper alternative. Explore whether there are cheaper ways to access phone service than what you pay now. A little frugality now could make a difference in the future.

Making a big difference over time

Nobody will claim that saving an extra $5 here or there will create instant financial security. But a patient, consistent strategy of saving and investing more for your retirement or other financial goals can truly add up.

If you can save an extra $100 per month and invest it in a tax-deferred IRA or workplace retirement plan earning an average annual return of seven percent per year, that money would accumulate to a before-tax value of:

????? $17,409 in ten years

????? $52,394 in 20 years

????? $122,699 in 30 years.

If you increase your contribution to $300, it would, based on the same return and tax assumptions, grow to a value of approximately $368,000 in 30 years. Saving an extra $500 per month with the same assumptions would accumulate $613,495 in retirement assets in 30 years.

Extra effort now could significantly improve your financial standing in retirement. Consider meeting with a financial advisor to help you get started and explore more saving and investment options.

Source: http://news.ellwoodcity.org/2012/07/24/finding-extra-money-to-save-for-retirement/

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Felix Baumgartner Jumps From 18 Miles Up. Next: the World Record

Now just the big jump remains.

Wednesday, daredevil Felix Baumgartner jumped from nearly 100,000 feet up, cruised to more than 500 miles per hour, and landed safely near Roswell, N.M., the AP reports. Baumgartner flew for nearly four minutes after jumping from his giant helium balloon before pulling his chute.

This success is the next-to-last jump for the Red Bull Stratos mission. In the coming weeks, Baumgartner intends to complete his plan of jumping from 125,000 feet, or about 23 miles up. That would shatter the current record of 19.5 miles, set in 1960 by Air Force man Joe Kittinger (who has been coaching Baumgartner during his preparations.)

While we anticipate Felix's final attempt, you can catch up on what he's done so far with our photo tour of the capsule, our interview with Baumgartner, our 2010 cover story on the jump, and our illustration of how the record-setting space dive will unfold.

Source: http://www.popularmechanics.com/how-to/blog/felix-baumgartner-jumps-from-18-miles-up-next-the-world-record-11016448?src=rss

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Wednesday, July 25, 2012

The entire list of our Rome, Italy (CIA) fares

Sorry, there are no longer active fares to Rome that meet our Dealhounds' standards.

Send me a low fare alert to Rome

Our Dealhounds find some pretty amazing fares ? but they sell out fast! Sign up now and we'll send you an alert whenever we find a great fare.

Search for flights to Rome, Italy (CIA)

Source: http://www.airfarewatchdog.com/cheap-flights/to-rome-italy/1201/?airport_code=cia

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OS X Mountain Lion goes on sale tomorrow

Apple has announced in their Q3 financial earnings press release that OS X 10.8 Mountain Lion will be released tomorrow. It will be available in the Mac App Store for $19.99 to all Snow Leopard and Lion users.

We?re thrilled with record sales of 17 million iPads in the June quarter,? said Tim Cook, Apple?s CEO. ?We?ve also just updated the entire MacBook line, will release Mountain Lion tomorrow and will be launching iOS 6 this Fall. We are also really looking forward to the amazing new products we?ve got in the pipeline.

Mountain Lion brings even more of the iPad and iOS experience back to the Mac, including renamed Contacts and Calendar apps, and new Reminders, Dictation, AirPlay, Game Center, and Notification Center, and unique features like PowerNap and Gatekeeper.

Are you planning to upgrade to Mountain Lion or will you be sitting this one out?



Source: http://feedproxy.google.com/~r/TheIphoneBlog/~3/m1sOaA8AG14/story01.htm

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Monday, July 23, 2012

Extreme Weight Loss Tips That Could Hurt You - Health & Fitness ...

If you wish to lose a lot of weight inside a short time-frame, there are extreme weight loss tips that give quick results. These tips should support you to achieve your desired weight quickly but they could also have adverse health after-effects. If you become desperate to have fast results, here are some extreme weight loss tips you are able to consider.

If you want to drastically lose weight, one of the most effectual extreme weight loss techniques is to take part in in a boot camp program. In a boot camp, you group up with others in your attempt to lose weight. Accountability gives ambition and the array of workouts means you will never be bored. You can also follow an intense exercise plan that gives extreme results. Unfortunately, over exercising could have negative after-effects like injuries, burnouts and nausea. You also ought to be very determined to go through these varieties of programs.

Extreme dieting is the most popular of all extreme weight loss techniques. One could follow a restrictive calorie diet, a liquid only diet or a protein only diet. Most of the restrictive diet programs involve staying cleer of high calorie food groups such as carbs and fats. The dieting methods are effectual weight loss tips however they also have negative after-effects. Starvation diets cause great cravings and binge eating. They are able to also create nutritional deficiencies and medical conditions like the deadly anorexia. Starving yourself also destroys the body?s metabolism as the body stores calories. It is additionally hard to stick to these kinds of diets for a extended time and it makes it exhausting to maintain the results for a long time.

This is not only an extreme weight loss strategy but it is also a risky one. There are various surgery options along with liposuction and stomach stapling. The goal of stomach stapling is to cut down the size of the stomach. This means that someone eats less and still gets satisfied. This surgery can cause serious stomach infections and is solely those desperate to lose weight like someone that is very obese. The aim of liposuction is to remove excess fat from the stomach. If you agree to take this option, make sure you go to a reputable doctor. On the other hand, I don?t advise this alternative.

There are pills that cut down the appetite so that someone eats less. These pills affect the brain and some of them act as laxatives. While they can lead to rapid fat loss, they can also become habit-forming and bad to your health. If you decide to use this method, make certain you only take pills prescribed by a doctor. There are a lot of weight loss scams available that promise magical weight loss pills and supplements without delivering results.

The correct strategy to stay fit and sustain healthy weight is to workout and follow a nutritious diet. If you decide to follow any one of the tips, it is critical to talk over with another the health implication of the option with a qualified medical professional. While following the extreme weight loss techniques causes extreme fat loss results, they are not nutritious strategies to lose weight.

Should you desire to start a health challenge you should not go to these extreme risks. Just find some easy extreme weight loss tips that should help you in achieving your goals and maintain your weight for the long term.

Source: http://www.health-fitness.co.za/2012/07/22/extreme-weight-loss-tips-that-could-hurt-you/

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I feel My Pet dog Has got Salmonella Accumulation ? What Need to I ...

Because the subject matter of pets in warm cars is becoming progressively more additional talked about in recent years,dog apparel, so hold the measures to protect pets. Currently you will find 14 states which have regulations with stiff penalties for leaving an bestial unattended inside of a auto. Further than the state amount, there are lots of municipalities which have adopted their very own laws relating to cruelty to animals and particularly dogs in vehicles. These penalties can range from fines to approximately a yr of jail time. You will also find suggestions to the action that may be taken by stability personnel or legislation enforcement that happen to be referred to as to reply to an bestial in distress simply call. Most often,dog clothes, the regulation enforcement is allowed to use ?necessary force? to get rid of the animal with the circumstance.
In the event your doggy only features a moderate case with the infection, your vet may perhaps decide to offer him intravenous fluids as a substitute. Fluids could probably comprise electrolytes (as salmonella would build an electrolyte imbalance with your dog) that ought to rehydrate your puppy.
Christina Graham is a veterinarian surgical treatment tech and/or pet groomer for over fifteen many years. And in people ages has attained an invaluable expertise regarding a pet dogs well being and diet. That?s why she designed DogVitaminFacts.com to dispel any false myths and offer an genuine beneficial perception in the benefits of fine nutrition and a excellent doggy vitamin nutritional supplement in your canine. Check out DogVitaminFacts.com to learn more.
There have already been latest information a couple of pet food organization that?s recalling some it is really dog food items on account of stories of salmonella poisoning. The poisoning was not only passed on into the dogs but to their owners at the same time. So is there everything which might be completed in the event your canine has Salmonella poisoning?
Salmonellosis is an infection that can be discovered in puppies or cats which have been contaminated together with the Salmonella virus. It?s also a bacterium that?s regarded to get transmitted to humans likewise. This may result in intestinal infections amongst animals and humans. This will be dangerous,dog shoes, specifically to pregnant females as it might lead to an unlucky abortion.
Not surprisingly, to avoid salmonella from ever infecting your dog, often choose to give your doggy a top quality pet food. You will discover also numerous doggy foods available that may be low-cost, but never give them the correct vitamins your canine needs, so it?s best to stay to dependable significant superior pet food items that supply superior nutrition and elements. It is additionally recommended that you just provide your pet dog by using a excellent doggy vitamin. This not merely inhibits infection and health conditions,dog clothing, but would also improve your dog?s immune method.
Indicators you?ll want to start to appearance out for are vomiting, diarrhea, (the diarrhea can possibly have blood in it in addition and would emit a really bad odor) reduction of appetite, a higher fever, inner thoughts of weak point, stomach agony, lethargy and perhaps despair.
You need to get your canine into the vet to be able to get him the very best care that he wants. Your vet could prescribe some antibiotics on your doggy if he has intense poisoning. You?ll want to give the prescribed antibiotics routinely although you think that the infection has gone absent. Some canines that have actually critical cases involve blood transfusions or plasma transfusions.dog shoes

Source: http://uk-answers.ru/?p=10476

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